Thymosin Alpha 1 from Thymosin Alpha Labs is a synthetic 28-residue acetylated peptide, supplied as a white lyophilized powder in 5 mg vials. Every lot is independently tested, and its results are published as a lot record.
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Specifications and current testing status in one place.
Thymosin Alpha 1 (thymosin α1) is a 28-residue peptide, acetylated at its N-terminus, that was first isolated from thymosin fraction 5, an extract of calf thymus. It is cut from the precursor protein prothymosin α. The sequence is strongly acidic, with seven glutamates and three aspartates against four lysines, so the molecule carries a large net negative charge at neutral pH, and it has no aromatic residues and no cysteine. Thymosin α1 is studied in immunology research for its effects on T-cell maturation in laboratory models.
Thymosin Alpha Labs supplies it as a lyophilized powder in 5 mg vials through Klow.bio. Each lot is tested by an independent laboratory for HPLC-UV purity, LC-MS identity and net content, and its certificate is published here.
Ac-Ser1 is acetylated and Asn28 ends in a free acid. With no tryptophan, tyrosine or phenylalanine, the peptide absorbs only weakly above 220 nm, so HPLC purity is read at the peptide-bond wavelength.
complete Thymosin Alpha 1 specifications.
Store sealed, dry and protected from light at the temperature stated on the vial label. Allow a cold vial to reach room temperature before opening. Lyophilized material absorbs moisture from the air, and absorbed moisture restarts the reactions that drying slows, so keep vials sealed until needed. Storage and stability guide.
| Product | Thymosin Alpha 1 |
|---|---|
| Type | Synthetic 28-residue acetylated peptide |
| Molecular formula | C129H215N33O55 |
| Molecular weight | 3108.32 g/mol (average) |
| Length | 28 residues |
| Sequence | Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN |
| N-terminus | Acetyl (Ac-Ser1) |
| C-terminus | Free acid (Asn28) |
| CAS number | 62304-98-7 |
| Form | White lyophilized powder |
| Vial sizes | 5 mg |
| Purity specification | ≥95% (HPLC-UV) |
| Storage | Store sealed, dry and protected from light at the temperature stated on the vial label. Allow a cold vial to reach room temperature before opening. |
| Designation | Research use only |
Price: $19.99, with bundle pricing (2 vials save 5%; 3 or more vials save 10%). Current prices are always on klow.bio.
| Vial size | Current lot | Purity (HPLC-UV) | Identity | Net content | Endotoxin | Certificate | Order |
|---|---|---|---|---|---|---|---|
| 5 mg | Certificate pending | Order 5 mg | |||||
Ordering and shipping. Thymosin Alpha 1 is sold through klow.bio, operated by Klow Labs LLC. Orders ship the next business day. Same-day cutoff is 4:00 PM CT, with overnight and 2-day options at checkout. See shipping and returns.
All testing is performed by Freedom Diagnostics, an independent laboratory, on every lot.
Reversed-phase high-performance liquid chromatography separates the sample's components by hydrophobicity, and a UV detector records each as a peak. Purity is the main peak's area as a percentage of all detected peak area.
Limits: does not identify the peak, and impurities that co-elute or absorb weakly in UV can be under-counted. More on HPLC
The separated sample enters a mass spectrometer via electrospray ionization, which gives the molecule one or more charges. The observed ions, near m/z 1555 (2+) and 1037 (3+), are matched against values calculated from Thymosin Alpha 1's molecular weight of 3108.32.
Limits: confirms molecular weight, not amino-acid order.
The laboratory quantifies the main compound in the tested vial against a standard. It is reported in milligrams next to the labeled vial size.
Limits: measured on the vial tested; other vials from the same lot are expected to be similar but are not individually measured.
Identity by LC-MS, with the laboratory’s reference numbers.
Certificate in progress. The current batch is with the testing laboratory. Its certificate of analysis will be published here, with purity, identity and net content, as soon as the report is issued. Current availability on Klow.bio.
Thymosin Alpha 1 is a synthetic 28-residue acetylated peptide. Thymosin Alpha Labs supplies it as a white lyophilized powder in 5 mg vials, with an independent certificate of analysis for every lot.
Thymosin Alpha 1 research material is Thymosin Alpha 1 supplied for laboratory research, sold by lot, with each lot's identity, purity and net content documented by an independent laboratory in a published certificate of analysis.
The molecular formula is C129H215N33O55 and the average molecular weight is 3108.32 g/mol. The peptide has 28 residues.
Store sealed, dry and protected from light at the temperature stated on the vial label. Allow a cold vial to reach room temperature before opening.
The current batch is with the laboratory. Its certificate will be published on this site when the report is issued.
Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN: 28 residues with an acetylated N-terminus, C129H215N33O55, 3108.32 g/mol.
Current Thymosin Alpha 1 research material availability is provided through Klow.bio, the purchasing platform operated by Klow Labs: https://klow.bio/product/thymosin-alpha-1/ Lot records, testing information and certificates of analysis are published on thymosinalpha.bio so they can be reviewed before purchasing.
Yes. Purchasing information and current availability for Thymosin Alpha 1 research material are provided through Klow.bio: https://klow.bio/product/thymosin-alpha-1/
Yes. Every lot is tested by Freedom Diagnostics, an independent laboratory, for HPLC-UV purity, LC-MS identity and net content. The stated release specification is ≥95% HPLC-UV purity with identity confirmed by LC-MS.
Enter the lot number from your vial label at thymosinalpha.bio/verify/ to see that lot's results. To confirm with the laboratory directly: Scan the Freedom Diagnostics QR code printed on the certificate, then search for klow.bio under the Company tab to view the laboratory record.
The current price is $19.99, with bundle pricing (2 vials save 5%; 3 or more vials save 10%). Current pricing is always listed on Klow.bio.
Orders ship the next business day. Same-day cutoff is 4:00 PM CT, with overnight and 2-day options at checkout.
Retention time, peaks, area normalization and every lot's HPLC result.
DocumentationEvery section of a Thymosin Alpha 1 COA, red flags, and what it does and doesn't prove.
Analytical methodsPurity vs. content vs. net content, impurity sources and comparing claims.
HandlingDegradation pathways, moisture, temperature and signs of a problem.
5 mg vials. The current batch's certificate is in progress. Current purchasing is available through Klow.bio.